Mice and transgenic mice are the most frequently used animal models in biomedical studies. However antibodies against mouse protein are difficult to be raised in mice themselves. Therefore, antibodies from other species have to be considered and rat monoclonal antibodies are a good choice.
Rat monoclonal antibodies can not only be used in mouse models, they can also be used as research or diagnostic tools in an identical manner to any murine antibodies. In addition, they can be used in combination with murine antibodies and different secondary antibody combinations for multiple analyses such as co-localization assays.